[HTML][HTML] Src family kinases and pulmonary fibrosis: A review
H Li, C Zhao, Y Tian, J Lu, G Zhang, S Liang… - Biomedicine & …, 2020 - Elsevier
… via a β3 integrin-, c-Src-, and p38 MAPK-dependent pathway [… by regulation of Fyn activation
by adaptor protein Unc-119 [75]. … approach for inhibiting myofibroblast differentiation in PF. …
by adaptor protein Unc-119 [75]. … approach for inhibiting myofibroblast differentiation in PF. …
Aberrant expression of miR-125a-3p promotes fibroblast activation via Fyn/STAT3 pathway during silica-induced pulmonary fibrosis
Q Xu, Y Liu, H Pan, T Xu, Y Li, J Yuan, P Li, W Yao… - Toxicology, 2019 - Elsevier
… -125a-3p regulates Fyn mRNA as well as its protein expression level through interaction with
its 3… of miR-125a-3p that leads to myofibroblast differentiation of fibroblasts. On the contrary, …
its 3… of miR-125a-3p that leads to myofibroblast differentiation of fibroblasts. On the contrary, …
The RAS-interacting chaperone UNC119 drives the RASSF6–MDM2–p53 axis and antagonizes RAS-mediated malignant transformation
T Shimizu, T Nakamura, H Inaba, H Iwasa… - Journal of Biological …, 2020 - ASBMB
… with RASSF6 and regulates RASSF6-mediated apoptosis. In this study, using several human
… However, when we performed immunoprecipitation with anti-UNC119 antibody using the …
… However, when we performed immunoprecipitation with anti-UNC119 antibody using the …
NORAD lentivirus shRNA mitigates fibrosis and inflammatory responses in diabetic cardiomyopathy via the ceRNA network of NORAD/miR-125a-3p/Fyn
Y Liu, Y Zhu, S Liu, J Liu, X Li - Inflammation Research, 2021 - Springer
… in myofibroblast differentiation [38]. It has been reported that Fyn deficiency inhibits fibrosis
by down-regulating … Moreover, down-regulation of Fyn up-regulates and activates Nrf2 and …
by down-regulating … Moreover, down-regulation of Fyn up-regulates and activates Nrf2 and …
[PDF][PDF] Role of Fyn and the interleukin-6-STAT-3-autophagy axis in sarcopenia
T Sasaki, E Yamada, R Uehara, S Okada, H Chikuda… - Iscience, 2023 - cell.com
… Furthermore, we 57 examined the physiological role of Fyn in regulating … Unc119 regulates
myofibroblast differentiation through the activation of 725 Fyn and the p38 MAPK pathway…
myofibroblast differentiation through the activation of 725 Fyn and the p38 MAPK pathway…
Identification of key pathways and genes in the progression of silicosis based on WGCNA
J Lv, J Xiao, Q Jia, X Meng, Z Yang, S Pu, M Li… - Inhalation …, 2022 - Taylor & Francis
… ) can stimulate the induction of α-SMA and myofibroblast differentiation by TGF-β in lung …
inhibitor of activated STAT 4 (PIAS4) mediates fibrosis by regulating the TGF-β/Smad pathway: 1…
inhibitor of activated STAT 4 (PIAS4) mediates fibrosis by regulating the TGF-β/Smad pathway: 1…
Gα12/13 signaling in metabolic diseases
… with the tyrosine kinase Fyn enhances Gα q/11 signaling. … Casein kinase 2 phosphorylates
UNC119, and this … as a kinase regulated by the Gα 12 signaling pathway during …
UNC119, and this … as a kinase regulated by the Gα 12 signaling pathway during …